Hi,
Things to check

as suggested by peterpiper make sure ALL your fingers cover their respective holes properly as leaks on the bottom hand can cause octave jumps when opening and closing the thumb hole
are all joints sealed properly
then check with another reed to eliminate reed problems
if it disappears then try
is the reed split anywhere (check with a magnifying glass)
has a bit of muck got between the blades
is the reed airtight at the sides
does it seal into the reed socket (needs to be airtight too)
has a corner been sanded down too much or a sliver knocked off by accident
good luck and take care
Dave